Overview of Piperlongumine
Piperlongumine (PL) is one of a few natural products identified to have the ability to selectively kill SCs . Compared to other known senolytic agents, piperlongumine has the advantage of low toxicity, an excellent PK/PD profile, and oral bioavailability. This natural compound has been calling attention of scientific community because of its biological activities such as antitumor, antimetastatic, antiplatelet aggregation and anxiolytic....