spike-protein-6vsb

Emerging Sars-CoV-2 Variants

The names of the first strain of the virus, went from --"Wuhan virus" to "novel coronavirus-2019" to "COVID-19" virus, and now official designation is: "SARS-CoV-2 "(severe acute respiratory syndrome coronavirus 2).

Image Left: pdb:6VSB -Prefusion 2019-nCoV spike glycoprotein with a single receptor-binding domain up. Released: 2020-02-26 in Protein Data Bank as 6VSB. Image shows the trimer of the spike protein with one of the three receptor-binding domains (RBDs) rotated up in a receptor-accessible conformation.

The virus mutated rapidly first in China to the more virulant D614G mutation which traveled to Europe and since became the dominant strain in the US. More recently even more transmissible variants have ocurred namely:

D614G mutation
B.1.1.7 and B.1.525 UK variant
B.1.351, South Africa (E484K variant
Brazil P.1variant
B.1.427/B.1.429, California Q677P Mutation
B.1.526, NY E484K or S477N Mutations

===>Start with the Novel Sars-CoV-2 Structure and Properties

See also: Why is simple soap most effective in destroying coronoavirus -- SARS-CoV-2?


photosynthetic reaction center showing chlorophyll special pair

Why Study Molecules?

Just as the 20th century was marked by the development of electricity, telephones, aviation, computing, and private motor vehicles, the 21st century will be marked by significant progress in a broad spectrum of technologies, among them: molecular computing, genomics, rational drug design, and alternative energy. What will be common to all these new technologies?

They will all be possible because of a greater understanding of The World of Molecules.

Image Left: Photosythetic Reaction Center (1PRC PDB) showing Chlorphyll "Special Pair". Image shows Chorophyll molecules (green); Pheophytin molecules (grey); dihydroneurosporene(yellow); quinones (red). See: Molecules of Color-- Photosynthetic Pigments

surose molecule

Food Molecules

What are foods? Read about Fats, Fatty acids, Trans Fatty Acids, Proteins, Amino Acids, Carbohydrates, Phenolics, Aroma and Taste

curcumin molecule

Antioxidants

Many compounds have been shown to have positive antioxidants effects . Read about Carotenoids, Vitamin E, Resveratrol, Epicatechin, Vitamin C, Proanthocyanidins...

folic acid molecule

Supplements

What is a food supplement? Read about the B vitamins, Vitamin D, Quercetin, Resveratrol, Vitamin E, Vitamin K, Vitamin C, Herbs and Botanicals, Amino Acids ...

DNA molecule

Molecules-Life

Molecules of Life --DNA sometimes called the "molecule of heredity", is the primary chemical component of chromosomes and is the material of which genes are made.

serotonin molecule - ball and stickModel

Molecules of Emotion

What are emotions? What molecules make you feel the way you do? Molecules of Emotion are: Adrenaline, Testosterone, Serotonin, Dopamine.

Prion Molecule -- Ribbon Structure Model

Molecules of Disease

Mad Cow Disease, Heart Disease, Cancer, Arthritis have one or several molecular causes. .. Cytokines, Hemoglobin S, Prions, Cholesterol,...

Penicillin Molecule --Ball and Stick Model

Drug Molecules

What is a drug? Read about Drug Molecules such as: Aspirin, AZT, Benadryl, Nicotine, Penicillin, Prozac, Ibuprofen, Lipitor, Novocaine, Oxycodone, Linzess, Ritalin.. see 3D structures..

DDT Molecule -- Ball and Stick Model

Pesticides and Insecticides

What are pesticides and Insecticides, Read about common Pesticide and Insectides such as: DDT, Pyrethrum,Cypermehtrin, Rotenone....

acetone molecule -- Ball-and-Stick model

Solvent Molecules

What is a solvent? Water, organic compounds, such as Benzene, Turpentine,, Ethanol, Benzene, Acetone.

hexane molecule ball-and-stick model

Fuel Molecules

What is a Fuel? Read about Fuel Molecules such as: Methane, Ethane, Propane, Pentane, Octane, Decane, Butane, Ethanol..

chlorophyll molecule from photosythetic protein

Molecules of Color

What are pigments and dyes. Read about: Beta-Carotene, Astaxanthin, Zeaxanthin, Turmeric, Chlorophyll...

Nanotube Molecular Steucture -- Wireframe Model

Materials

Read and view molecular structures for materials such as: Diamond, Fullerene, Cotton, Styrene, Graphite, Nylon, Teflon, Plexiglass...

K-12 molecular modeling

Molecules for K-12

Activities designed to introduce K-12 (middle and high school) students to the world of molecules -- Jsmol is now used. Many activities contain javascript assessments.

Nanotube Molecular Steucture -- Wireframe Model

Explain it with Molecules

How does soap work, why does ice float, what is the geometry of methane, how does caffeine work in the brain, how to drugs work, diamond vs. graphite and more...

acid and base molecules

Acid and Bases

Common acid and base molecules--HCl, Acetic Acid, Lactic Acid, Sodium bicarbonate, sodium hydroxide...

jsmol showing methane molecule

3-D using Jsmol

See molecules interactively using Jsmol-- hydrocarbons, drugs, amino acids, fats and fatty acids, photosynthetic molecules ...


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